VE202 is an orally administered, rationally-designed bacterial consortium candidate being developed for the potential treatment of inflammatory bowel disease (IBD). VE202 consists of clonal human commensal bacteria strains selected for their ability to impact the number and activity of regulatory T cells in the gut mucosa and manufactured under CGMP conditions. It is produced from pure, clonal cell banks, which yield a standardized drug product in powder form and bypass the need to rely on direct sourcing of fecal donor material of inconsistent composition. The foundational research underlying VE202 led by Vedanta Biosciences’ co-founder Kenya Honda, M.D., Ph.D. of Keio University School of Medicine was published in Science and two additional publications in Nature (Atarashi et al. 2013Furusawa et al. 2013)

In a Phase 1 study, VE202 was shown to be generally safe and well tolerated at all doses and demonstrated durable and dose-dependent colonization.

Vedanta is currently enrolling participants into a Phase 2 study of VE202 for patients with IBD. For more information about the study including contact details, please visit the COLLECTiVE202 study website and/or