Intellectual Property

A Foundational Intellectual Property Estate In The Human Microbiome Field

Vedanta has developed a key Intellectual Property (IP) portfolio in the human microbiome field. The portfolio includes fundamental patents (the “Honda patents”) covering compositions and therapeutic uses of products containing bacteria belonging to Clostridium clusters IV and XIVa, as well as spore-forming fractions obtained from stool samples. The European Honda patent EP2575835 was recently upheld in opposition proceedings at the EPO (View Press Release). Bacteria within clusters IV and XIVa are among the most abundant colonizers of the human intestine and they play an important role in human health, including regulating immune responses. Our IP estate includes issued patents in the major pharmaceutical markets (US, Europe, and Japan) with priority dates going back to 2010. Our patents provide coverage through at least 2031, with some patents extending coverage through at least 2037. This Intellectual Property portfolio puts Vedanta in a unique leadership position in the microbiome field and allows us to support our internal programs as well as enable our partners to advance bacterial consortia therapeutics.

Vedanta’s European and U.S. Patents

Patent Title Applicant/Assignee Country Issue Date
10,350,250 Treatment of Clostridium Difficile Infection Vedanta Biosciences Inc. US Jul 16, 2019
10,342,832 Human-derived Bacteria that Induce Proliferation or Accumulation of Regulatory T Cells University of Tokyo; School Corporation, Azabu Veterinary Medicine Educational Institution US Jul 09, 2019
10,328,108 Composition for Inducing Proliferation or Accumulation of Regulatory T Cell The University of Tokyo US Jun 25, 2019
10,322,150 Composition for Inducing Proliferation or Accumulation of Regulatory T Cell The University of Tokyo US Jun 18, 2019
10,300,137 Compositions and Methods for Induction of TH17 Cells Riken; The University of Tokyo; School Corporation, Azabu Veterinary Medicine Educational Institution US May 28, 2019
10,183,045 Human-Derived Bacteria That Induce Proliferation Or Accumulation Of Regulatory T Cells University of Tokyo; School Corporation, Azabu Veterinary Medicine Educational Institution US Jan 22, 2019
10,130,695 Compositions Containing Combinations Of Bioactive Molecules Derived From Microbiota For Treatment Of Disease Vedanta Biosciences Inc.; Riken US Nov 20, 2018
10,092,603 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cell The University of Tokyo US Oct 09, 2018
10,064,904 Treatment Of Clostridium Difficile Infection Vedanta Biosciences Inc. US Sep 04, 2018
10,058,578 Human-Derived Bacteria That Induce Proliferation Or Accumulation Of Regulatory T Cells University of Tokyo; School Corporation, Azabu Veterinary Medicine Educational Institution US Aug 28, 2018
10,052,353 Human-Derived Bacteria That Induce Proliferation Or Accumulation Of Regulatory T Cells University of Tokyo; School Corporation, Azabu Veterinary Medicine Educational Institution US Aug 21, 2018
9,999,641 Treatment Of Clostridium Difficile Infection Vedanta Biosciences Inc. US Jun 19, 2018
9,833,483 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US Dec 05, 2017
9,827,276 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US Nov 28, 2017
9,808,519 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US Nov 07, 2017
9,801,933 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US Oct 31, 2017
9,764,019 Compositions Containing Combinations Of Bioactive Molecules Derived From Microbiota For Treatment Of Disease Vedanta Biosciences, RIKEN US Sep 19, 2017
9,662,381 Composition for Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US May 30, 2017
9,649,345 Human-Derived Bacteria That Induce Proliferation Or Accumulation Of Regulatory T Cells University of Tokyo; School Corporation, Azabu Veterinary Medicine Educational Institution US May 16, 2017
9,642,881 Human-Derived Bacteria That Induce Proliferation Or Accumulation Of Regulatory T Cells University of Tokyo; School Corporation, Azabu Veterinary Medicine Educational Institution US May 09, 2017
9,642,882 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US May 09, 2017
EP2575835 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo EP Oct 19, 2016
9,433,652 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US Sep 06, 2016
9,421,230 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US Aug 23, 2016
9,415,079 Composition For Inducing Proliferation Or Accumulation Of Regulatory T Cells The University of Tokyo US Aug 16, 2016